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ANTIOXIDANT
POLYPHENOLS & HUMAN HEALTHCARE
Numerous laboratories in the past ten years have
shown that polyphenols extracted from olive oil have in vitro and
in vivo activity in preventing and/or reducing the deleterious effects
of oxygen-derived free radicals associated with numerous inflammatory
and stress related human and animal diseases. The absorption of
olive oil polyphenols in humans from the gastrointestinal apparatus
was recently confirmed and associated with a potentially significant
increase of antioxidant effect in vivo.
The antioxidant activity of polyphenols has shown
promising results with respect to:
ATHEROSCLEROSIS.
Oxidized low-density lipoproteins (LDL) contribute
to the progression of human atherosclerosis. Antioxidants have been
shown to prevent LDL modification. The beneficial effects of a Mediterranean
diet may be defined by the unique antioxidant properties of its phenolic
compounds.
ANTIMICROBIAL
ACTIVITY.
Olive polyphenols have been demonstrated to inhibit
or delay the rate of growth bacteria such as Salmonella, Cholerae,
Staphylococcus, Pseudomonas, and Influenza in vitro. These data
suggest a potential role of olive water polyphenol antioxidants
in promoting intestinal and respiratory human and animal wellness,
and as an antimicrobial food additive in pest management programs.
CANCER.
There is a growing body of evidence
that reactive oxygen species are involved in the etiology of fat-related
neoplasm, especially in patients suffering from predisposing inflammatory
conditions where high quantities of reactive oxygen are produced.
Recent studies have shown that the abundant phenolic antioxidant
fractions of olive oil have a potent inhibitory ability on reactive
oxygen species associated with colon and breast pathologies.
OXIDATIVE
STRESS FROM PASSIVE SMOKING.
Recent studies which involve administration of
the phenolic fraction from olive water in rats exposed to oxidative
stress from secondary smoke, show a dramatic reduction of stress
and protective activity by polyphenols in the diet.
SKIN
DAMAGE AND PHOTOPROTECTION.
The skin damage produced by overexposure to sun
rays and environmental stress is related to the destructive activity
of free oxygen-related radicals produced by skin cells. Polyphenolic
components of olive oil have been compared to traditional antioxidants,
such as tocopherols, used by the cosmetic and pharmaceutical industry
to prevent skin damage. Results show polyphenols as having the highest
activity as radical scavengers.
*These statements
have not been evaluated by the Food and Drug Administration. This
product is not intended to diagnose, treat, cure or prevent any
disease.
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